Dr.Hany Marei CV

Brief Overview

Expert Evaluator for the call  HORIZON-EIC-2021-PATHFINDERCHALLENGES-01 (Modulation and stimulation of Brain activities).

Chair of Academic Veterinary Committee for promotion of Assistant Professors and Professors (Anatomy, Histology, Physiology) at the Supreme Counsel of the Egyptian Universities (2022 till 2025).

Chair of Academic Veterinary Committee for promotion of Assistant Professors and Professors (Anatomy, Histology, Physiology) at the Supreme Counsel of the Egyptian Universities (2018 till 2022).

Head of Cytology and Histology Department, Faculty of Veterinary Medicine, Mansoura University, Egypt (1996 – 2015, and from 2018-present),

Project Manager, Biomedical Research Center, Qatar University (May 2015- March 2018)

 Prof. Dr. Hany Marei has got his PhD as Joint Channel system between Virginia-Maryland Regional Collage of Veterinary Medicine, Virginia Polytechnical Institute and State University, USA, and Suze Canal University, Egypt at 1994. He is a full professor since 2005.

From 2012 -2015 he served as a member for Veterinary Academic Committee for promotion of Assistant Professors and Professors at the Supreme Counsel of the Egyptian University.

From May 2015 he moved to Qatar where he worked as a Research Professor and Project Manager for Biomedical Research Center (BRC) at Qatar University (QU). During this period he published more than 25 international publications, awarded three major projects, and participated as PI in two projects related to Qatar Genome Projects, participated as members of several managerial committee  at QU such as Health Cluster taskforce committee, IBC committee, intellectual properties committee, and QU international Ranking Committee. He also participated in ISO 17025 Accreditation for two diagnostic molecular tests at BRC, QU. During the period between 2015-2018 he has attended 6 international conferences in USA, and Germany as well as an International Bioinformatics workshop in Lahore, Pakistan. He has organized more than 30 seminars tackling different topic in Biomedical Research. He has awarded two prestigious awards during the period between 2015-2018 (QU): best Research award in 2015, and honorably mentioned in the World Stem Cell Summit held in Atlanta. Georgia, 2015). He has participated in the organization of one international conference (International Conference for Pathogen at Human Animal Interface, ICOPHI), and two international workshops about Stem cells and Tissue Engineering and Emerging Pathogens.

His research interest lies in the field of stem cells, genomics of brain cancer & neurological diseases, and chimeric antigen receptor (CAR) T immunotherapy. He has experience in using multiple molecular techniques such stem cell culture, tissue banks, WGS, WES, gene expression, pathway analysis, RNA-seq, and single cells RNA-seq.

He published more than 60 papers of which 42 papers have been published in international web of sciences-indexed high impact factors journals such as PLOS, Genomics, Molecular Cancer, JCP, Oncotarget, Spinal Cord, Frontier in Neurology, Scientific Reports, Am J Stem Cells, J Cell Mol Med, Biochem Pharmacol, J Cell Physiol., Int J Nanomedicine, BMC Cancer, J Tissue Eng Regen Med., Front Neurol., J Diabetes Res., World J Emerg Surg., Future Microbiol., Mol Cancer).

In 2016, he published a book chapter (with Bentham Science Publishers (eBook series “Frontiers in Clinical Drug Research-Alzheimer Disorder; Vol. 4” entitled “Recent perspective about the amyloid cascade hypothesis and stem cell-based therapy in the treatment of Alzheimer’s disease”. He also published a book entitled “Human Olfactory Bulb Neural Stem Cells for Cell-based Therapy of Traumatic and Neurodegenerative CNS Disorders, LAMBERST, 2016.

Dr. Marei was participated as PI for a project entitled “Pharmacogenomics Landscape of Qatari Population” where he is involved in analysis of the whole genomic sequence data of more than 7000 Qatari.

In 2017, Dr. Marei has awarded a GCC-funded project in collaboration with Nizwa University, Oman entitled: “Use of patient-specific induced pluripotent stem cells (iPSCs) to study stroke in Qatar and GCC countries. The approved funds is $ 600000

In 2018, Dr. Marei has awarded a High Impact Project funded by QU entitled “ FCy Chimeric Receptor T cells and monoclonal antibodies for Glioblastoma multiform immunotherapy: In vitro and in vivo Studies”.  The approved funds is QR 800,500.

Dr. Marei is an editorial board member for:

American Journal of Current Genetics, Accounts of Biotechnology Research, Journal of Pediatric Oncology, Journal of Cytology and Tissue Biology, Journal of Stem Cell Research,  Journal of Alzheimer’s & Dementia, and Examines in Physical Medicine & Rehabilitation (EPMR), Research Advances in Brain Disorders and Therapy, Research & Investigations in Sports Medicine,    Current Chemical Genomics and Translational Medicine, Journal of Addiction & Criminology, Veterinary Medical Sciences Journal.

He serves as a reviewer in more than 20 web of science-indexed international indexed journals such as Journal of Tissue Engineering and Regenerative Medicine, BMC Veterinary Research, Cell Transplantation, Journal of Cellular Physiology, Scientific Reports, Anti-Cancer Agents in Medicinal Chemistry, Cell Cycle, Cells, Computational and Structural Biotechnology Journal, Current Drug Delivery, Frontiers of Medicine, HELIYON, Informatics in Medicine Unloacked, International Journal of Developmental Neuroscience, International journal of molecular sciences, Journal of Integrative Neuroscience, Neuroscience letter, Pharmaceutics, Polymers, and Science Progress.

He had defended more than 30 master and PhD thesis in Biomedical sciences, and reviewers for more than 400 papers in the field of Biomedical research and participated in the promotion of more than 50 Assistant Professors and Professors in the different fields of Biomedical Sciences.

Dr. Marei has secured more than $2 000 000 as fund for his research during the period between 2005-2018 from different national, and regional funding agencies such as STDF, Ministry of Higher Education, Qatar University, and NPRP programs.

From 2018 till present, he serves as a Chair of Veterinary Academic Committee for promotion of Assistant Professors and Professors at the Supreme Counsel of the Egyptian University. He participated in the promotion of more than 50 Assistant professors and professors in different field of academic veterinary sciences (Anatomy, Physiology, Histology).

He has obtained several prestigious awards at national, regional and international level such as:

• Mansoura University encouraging award (2004),
• Award of Excellence in international publication, Ministry of Higher Education, Egypt (2012),
• Award of Excellence in International Scientific Publication (Mansoura University, 2015),
• Honorable Mentioned Award in Stem Cell Summit, Atlanta, Georgia, USA (2015),
• Best research Award at Qatar University (2015)
• Best Poster Award at ARC2016^, QF

Mansoura University Award of Excellence in Scientific Researches (March 2019).

Detailed CV:

Hany El-Sayed Marei, M.V.Sc, Ph.D.

Ph.D. in Cytology and Histology, Joint between Virginia-Maryland Regional Collage of Veterinary Medicine, Virginia Tech, USA and Suez Canal University, Ismailia, Egypt (Nov. 1990 – May 1992)

Master of Cytology and Histology, Suez Canal University, Ismailia, Egypt (June. 1986- May 1990).

Bachelor of Veterinary Medicine (ranking 5th), Alexandria University, Collage of Veterinary Medicine (Sept. 1980 – June 1985)

Positions:

• Chair of the Scientific Committee for Academic Veterinary Sciences at the Supreme Council of Egyptian Universities from 2019 to 2020.
• Project Manager, QUBRC, Qatar (2015-present).
• PI for Lab Accreditation ISO 15189 Project.
• Professor, Head of Cytology and Histology Department, (2000-2015).
• Manager of Quality Assurance and Accreditation Unit.
• Manager of Central Veterinary Diagnostic lab.
• PI for Neural Stem Cells Project (STDF-funded).
• PI for Lab Accreditation ISO 17025 Project.
• PI of DVM and ISO 9001 Accreditation Project.
• Director for Central Lab for Veterinary Molecular Diagnosis, 20122015.
• Manager of E-Learning Unit, Faculty of Veterinary Medicine, Mansoura University, Egypt, 2008- 2012.

Positions:

• Project manager, Biomedical Research Center, Qatar University (May 2015-present).
• Department Head of Cytology and Histology, Mansoura University, Egypt (March. 2005-2015).
• Professor Cytology and Histology Department, Mansoura University, Egypt
• Acting as a Department Head of Cytology and Histology (Aug. 2000 – Mar. 2005)
• Assistant Professor of Cytology and Histology, Mansoura University (Oct. 1999- Feb 2005)
• Virginia-Maryland Regional Collage of Veterinary Medicine, Virginia Tech, USA (May. 1992 – May. 1994), Ph.D. in Cytology Joint between Virginia-Maryland Regional Collage of Veterinary Medicine, Virginia Tech, USA and Suez Canal University, Ismailia, Egypt (Nov. 1990 – May 1992)
• Assistant Lecturer of Cytology and Histology, Suez Canal University, Ismailia, Egypt (June. 1986- May 1990).
• Bachelor of Veterinary Medicine (ranking 5th), Alexandria University, Collage of Veterinary Medicine (Sept. 1980 – June 1985)

Management and Committee Member at Qatar University

• Member of Thematic Taskforce for Health Cluster, Qatar University, 2015.
• Member of committee for Interdisciplinary Graduate Research Institute Initiative”, Qatar University, 2016
• Member of Research International Ranking Committee, Qatar University, 2016.
• Member of the Institutional Bio-safety Committee, Qatar University, 2016.

Teaching Experiences (Courses Taught):

• Histology for Clinical Pharmacy (Faculty of Pharmacy, Mansoura University, Egypt).
• Cytology and Histology for Veterinary Students (Faculty of Veterinary Medicine, Mansoura University, Egypt).
• Cytology and Histology for Veterinary Students, Virginia-Maryland Regional Collage of Veterinary Medicine, Virginia Polytechnic
  Institute and State University, Blacksburg, Virginia, USA.
• Practical Histology for first year veterinary medical students at Virginia-Maryland Regional Collage of Veterinary Medicine, Virginia Polytechnic Institute and State University, Blacksburg, Virginia, USA.
• Histology for Clinical Pharmacy Students, Faculty of Pharmacy, Mansoura University.

Editor and Reviewer:

• Senior Editorial Board (SEB) Member of the American Journal of Current Genetics
• Editorial Board Member of Accounts of Biotechnology Research.
• Editorial Board Member of Journal of Pediatric Oncology
• Editor in Journal of Stem Cell Research.
• Journal of Cytology and Tissue Biology
• International Journal of Zoological Investigations.
• Henry Journal of Cytology and Histology
• Journal of Cytology and Histology
• Cancer Biology & Treatment
• SciTz Stem Cells Research & Therapy
• Journal of Stem Cell Research,
• Journal of Alzheimer’s & Dementia,
• Examines in Physical Medicine & Rehabilitation (EPMR), Research Advances in Brain Disorders and Therapy,
• Research & Investigations in Sports Medicine (http://crimsonpublishers.com/rism/editorial-board.php#)

Promotion Committees in Arab Countries:

• Reviewed Promotion file for King Abdul-Aziz University, Saudi Arabia.
• Reviewed Promotion file for El Basra University, Iraq.

1. Senior Editorial Board (SEB) Member of the American Journal of Current Genetics
2. Editorial Board Member of Accounts of Biotechnology Research.
3. Editorial Board Member of Journal of Pediatric Oncology
4. Editor in Journal of Stem Cell Research.
5. Journal of Cytology and Tissue Biology
6. International Journal of Zoological Investigations.
7. Henry Journal of Cytology and Histology
8. Journal of Cytology and Histology
9. Cancer Biology & Treatment
10. SciTz Stem Cells Research & Therapy
11. Journal of Stem Cell Research,
12. Journal of Alzheimer’s & Dementia,
13. Examines in Physical Medicine & Rehabilitation (EPMR),
14. Research Advances in Brain Disorders and Therapy,
15. Research & Investigations in Sports Medicine
16. Editor for Journal of Addiction & Criminology

Promotion Committees in Arab Countries:

• Reviewed Promotion file for King Abdul-Aziz University, Saudi Arabia.
• Reviewed Promotion file for El Basra University, Iraq.
• Reviewed Promotion file for Qatar University, Qatar.

Reviewer for International web of science Indexed Journals:

1. Scientific Reports
2. Cell Transplantation
3. Journal of Tissue Engineering and Regenerative Medicine
4. BMC Veterinary Research
5. Cell Biology International
6. Chemical Neuroanatomy
7. World Journal of Surgical Oncology
8. Anti-Cancer Agents in Medicinal Chemistry
9. Cell Cycle
10. Cells
11. Computational and Structural Biotechnology Journal
12. Current Drug Delivery
13. Frontiers of Medicine
14. HELIYON
15. Informatics in Medicine Unlocked
16. International Journal of Developmental Neuroscience
17. International journal of molecular sciences
18. Journal of Integrative Neuroscience
19. Neuroscience letter
20. Pharmaceutics
21. polymers
22. Recent Patents on Anti-Cancer Drug Discovery
23. Science Progress
24. Scientific Report

Promotion committee for Assistance professors and Professors

• Member of the promotion committee for Assistant Professors and Professors, Supreme Counsel of Universities, Egypt (2012-2015).
• Chair of the promotion committee for Assistant Professors and Professors, Supreme Counsel of Universities, Egypt (2018-2022).
• Reviewer for more than 500 papers.
• Evaluation Committee for 60 Assistant Professors and Professors.
• Reviews for five projects about Stem Cells.

Publications:

1. NO	Paper title	Journal	Impact factor	Publication date
   1	Cancer immunotherapy with immune checkpoint inhibitors (ICIs): potential, mechanisms of resistance, and strategies for reinvigorating T cell responsiveness when resistance is acquired Marei, H.E., Hasan, A., Pozzoli, G., Cenciarelli, C. Cancer Cell International, 2023, 23(1), 64	Cancer Cell International	6.435	2021
   2	Recent Prospective in CAR T-Based Therapy for Solid and Hematological Malignancies Marei, H.E., Cenciarelli, C. Biomedicines, 2023, 11(2), 627	Biomedicines	4.757	2021
   3	Multimodal targeting of glioma with functionalized nanoparticles Marei, H.E. Cancer Cell International, 2022, 22(1), 265	Cancer Cell International	6.435	2021
   4	Potential of antibody–drug conjugates (ADCs) for cancer therapy Marei, H.E., Cenciarelli, C., Hasan, A. Cancer Cell International, 2022, 22(1), 255	Cancer Cell International	6.435	2021
   5	Glioma extracellular vesicles for precision medicine: prognostic and theragnostic application Marei, H.E., Althani, A., Afifi, N., …D’Agnano, I., Cenciarelli, C. Discover Oncology, 2022, 13(1), 49	Discover Oncology	4.667	2022
   6	Exome sequencing of glioblastoma-derived cancer stem cells reveals rare clinically relevant frameshift deletion in MLLT1 gene Marei, H.E., Althani, A., Afifi, N., …Pozzoli, G., Cenciarelli, C. Cancer Cell International, 2022, 22(1), 9	Cancer Cell International	6.435	2021
   7	Editorial: Inflammation in ischemic stroke and novel therapeutic strategies for stroke treatment Marei, H.E., Yang, C., Cenciarelli, C., Jaillard, A. Frontiers in Neurology, 2022, 13, 1071557	Frontiers in Neurology	4.086	2021
   8	miRNome and Proteome Profiling of Small Extracellular Vesicles Secreted by Human Glioblastoma Cell Lines and Primary Cancer Stem Cells Cifola, I., Fratini, F., Cardinali, B., …Falcone, G., D’Agnano, I. Biomedicines, 2022, 10(8), 1886	Biomedicines	4.757	2021
   9	Effects of Rosemary Oil (Rosmarinus officinalis) supplementation on the fate of the transplanted human olfactory bulb neural stem cells against ibotenic acid-induced neurotoxicity (Alzheimer model) in rat Rezk, S., Lashen, S., EL-Adl, M., …Cenciarelli, C., Marei, H.E. Metabolic Brain Disease, 2022, 37(4), pp. 973–988	Metabolic Brain Disease	3.655	2021
   10	p53 signaling in cancer progression and therapy Marei, H.E., Althani, A., Afifi, N., …Giordano, A., Cenciarelli, C. Cancer Cell International, 2021, 21(1), 703	Cancer Cell International	6.435	2021
   11	Morphological Features of the Testis among Autoimmune Mouse Model and Healthy Strains Shouman, Z., Marei, H.E., Abd-Elmaksoud, A., …Ichii, O., Kon, Y. Microscopy and Microanalysis, 2021, 27(5), pp. 1209–1217	Microscopy and Microanalysis	4.099	2021
   12	Generation of gene edited hiPSC from familial Alzheimer’s disease patient carrying N141I missense mutation in presenilin 2 Marei, H.E., Althani, A., Afifi, N., …Pozzoli, G., Cenciarelli, C. Stem Cell Research, 2021, 56, 102552	Stem Cell Research	1.587	2021
   13	The therapeutic effects of tumor treating fields on cancer and noncancerous cells Mahgoub, E., Hussain, A., Sharifi, M., …Marei, H.E., Hasan, A. Arabian Journal of Chemistry, 2021, 14(10), 103386	Arabian Journal of Chemistry	6.212	2021
   14	Pandemic COVID-19 caused by SARS-CoV-2: genetic structure, vaccination, and therapeutic approaches Marei, H.E., Althani, A., Afifi, N., …Angelini, F., Cenciarelli, C. Molecular Biology Reports, 2021, 48(9), pp. 6513–6524	Molecular Biology Reports	2.742	2021
   15	Current progress in chimeric antigen receptor T cell therapy for glioblastoma multiforme Marei, H.E., Althani, A., Afifi, N., …Pozzoli, G., Cenciarelli, C. Cancer Medicine, 2021, 10(15), pp. 5019–5030	Cancer Medicine	4.711	2021
   16	Development of nitric oxide releasing visible light crosslinked gelatin methacrylate hydrogel for rapid closure of diabetic wounds Zahid, A.A., Augustine, R., Dalvi, Y.B., …Alfkey, R., Hasan, A. Biomedicine and Pharmacotherapy, 2021, 140, 111747	Biomedicine and Pharmacotherapy	7.419	2021
   17	Aspirin inhibits proliferation and promotes differentiation of neuroblastoma cells via p21Waf1 protein up-regulation and Rb1 pathway modulation Pozzoli, G., Petrucci, G., Navarra, P., Marei, H.E., Cenciarelli, C. Journal of Cellular and Molecular Medicine, 2019, 23(10), pp. 7078–7087	Journal of Cellular and Molecular Medicine	4.486	2019
   18	Aspirin inhibits cancer stem cells properties and growth of glioblastoma multiforme through Rb1 pathway modulation Pozzoli, G., Marei, H.E., Althani, A., …Sgambato, A., Cenciarelli, C. Journal of Cellular Physiology, 2019, 234(9), pp. 15459–15471	Journal of Cellular Physiology	5.546	2019
   19	Recent perspective on CAR and Fcγ-CR T cell immunotherapy for cancers: Preclinical evidence versus clinical outcomes Marei, H.E., Althani, A., Caceci, T., …Cenciarelli, C., Sconocchia, G. Biochemical Pharmacology, 2019, 166, pp. 335–346	Biochemical Pharmacology	4.960	2019
   20	Identification and mapping of brain natriuretic peptide in the normal ventricular myocardium of a desert-dwelling mammalian model, the camel (Camelus dromedarius): Immunohistochemical and ultrastructural study Osman, A.-H.K., Minamino, N., Marei, H.E. Journal of Cellular Physiology, 2019, 234(3), pp. 3067–3077	Journal of Cellular Physiology	5.546	2019
   21	Human olfactory bulb neural stem cells (Hu-OBNSCs) can be loaded with paclitaxel and used to inhibit glioblastoma cell growth Marei, H.E., Casalbore, P., Althani, A., …Bondiolotti, G., Pessina, A. Pharmaceutics, 2019, 11(1), 45	Pharmaceutics	4.421	2019
   22	A multi-cellular 3D bioprinting approach for vascularized heart tissue engineering based on HUVECs and iPSC-derived cardiomyocytes Maiullari, F., Costantini, M., Milan, M., …Bearzi, C., Rizzi, R. Scientific Reports, 2018, 8(1), 13532	Scientific Reports	4.011	2018
   23	Fabrication and in Vitro Characterization of a Tissue Engineered PCL-PLLA Heart Valve Hasan, A., Soliman, S., El Hajj, F., …Yalcin, H.C., Marei, H.E. Scientific Reports, 2018, 8(1), 8187	Scientific Reports	4.011	2018
   24	Incensole acetate prevents beta-amyloid-induced neurotoxicity in human olfactory bulb neural stem cells El-Magd, M.A., Khalifa, S.F., A. Alzahrani, F.A., …El-Taweel, F.M., Marei, H.E. Biomedicine and Pharmacotherapy, 2018, 105, pp. 813–823	Biomedicine and Pharmacotherapy	3.743	2018
   25	Advances in osteobiologic materials for bone substitutes Hasan, A., Byambaa, B., Morshed, M., …Mustafy, T., Marei, H.E. Journal of Tissue Engineering and Regenerative Medicine, 2018, 12(6), pp. 1448–1468	Journal of Tissue Engineering and Regenerative Medicine	3.319	2018
   26	VEGF-121 plasma level as biomarker for response to anti-angiogenetic therapy in recurrent glioblastoma Martini, M., de Pascalis, I., D’Alessandris, Q.G., …Pallini, R., Larocca, L.M. BMC Cancer, 2018, 18(1), 553	BMC Cancer	2.933	2018
   27	Potential of stem cell-based therapy for ischemic stroke Marei, H.E., Hasan, A., Rizzi, R., …Caceci, T., Shuaib, A. Frontiers in Neurology, 2018, 9(FEB), 34	Frontiers in Neurology	2.635	2018
   28	Differentiation of human olfactory bulb-derived neural stem cells toward oligodendrocyte Marei, H.E., Shouman, Z., Althani, A., …Cenciarelli, C., Casalbore, P. Journal of Cellular Physiology, 2018, 233(2), pp. 1321–1329	Journal of Cellular Physiology	4.522	2018
   29	Cholinergic and dopaminergic neuronal differentiation of human adipose tissue derived mesenchymal stem cells Marei, H.E.S., El-Gamal, A., Althani, A., …Thomas, C., Anwarul, H. Journal of Cellular Physiology, 2018, 233(2), pp. 936–945	Journal of Cellular Physiology	4.522	2018
   30	Nanoparticles in tissue engineering: Applications, challenges and prospects Hasan, A., Morshed, M., Memic, A., …Webster, T.J., Marei, H.E.-S. International Journal of Nanomedicine, 2018, 13, pp. 5637–5655	International Journal of Nanomedicine	4.471	2018
   31	Molecular characterization of olfactory bulb neural stem cells during proliferation and differentiation Saad, E.A., Marei, H.E.S., El-Magd, M.A., El-Fatiry, H.M. Journal of Applied Pharmaceutical Science, 2018, 8(1), pp. 087–092	Journal of Applied Pharmaceutical Science	1.41	2018
   32	Genetically unmatched human iPSC and ESC exhibit equivalent gene expression and neuronal differentiation potential Marei, H.E., Althani, A., Lashen, S., Cenciarelli, C., Hasan, A. Scientific Reports, 2017, 7(1), 17504	Scientific Reports	4.122	2017
   33	Nanotubes impregnated human olfactory bulb neural stem cells promote neuronal differentiation in Trimethyltin-induced neurodegeneration rat model Marei, H.E., Elnegiry, A.A., Zaghloul, A., …Cenciarelli, C., Hasan, A. Journal of Cellular Physiology, 2017, 232(12), pp. 3586–3597	Journal of Cellular Physiology	3.923	2017
   34	A Global Declaration on Appropriate Use of Antimicrobial Agents across the Surgical Pathway Sartelli, M., Kluger, Y., Ansaloni, L., …Mergulhão, P., Catena, F. Surgical Infections, 2017, 18(8), pp. 846–853	Surgical Infections	1.1	2017
   35	Antimicrobials: A global alliance for optimizing their rational use in intra-abdominal infections (AGORA). [World J Emerg Surg. 11, (2016) (33)] DOI: 10.1186/s13017-016-0089-y Sartelli, M., Weber, D.G., Ruppé, E., …Viscoli, C., Viale, P. World Journal of Emergency Surgery, 2017, 12(1), 35	World Journal of Emergency Surgery	3.198	2017
   36	PDGFRα depletion attenuates glioblastoma stem cells features by modulation of STAT3, RB1 and multiple oncogenic signals (Oncotarget (2016) 7 33 (53047-53063)) Cenciarelli, C., Marei, H.E., Felsani, A., …Olivi, A., Mangiola, A. Oncotarget, 2017, 8(22), pp. 36931	Oncotarget	5.168	2018
   37	Mesenchymal stem cells in the treatment of traumatic brain injury Hasan, A., Deeb, G., Rahal, R., …Gali, A., Sleiman, E. Frontiers in Neurology, 2017, 8(FEB), 28	Frontiers in Neurology	3.508	2017
   38	Role of the Gastrointestinal Tract Microbiome in the Pathophysiology of Diabetes Mellitus Sohail, M.U., Althani, A., Anwar, H., Rizzi, R., Marei, H.E. Journal of Diabetes Research, 2017, 2017, 9631435	Journal of Diabetes Research	2.885	2017
   39	The interference of Notch1 target Hes1 affects cell growth, differentiation and invasiveness of glioblastoma stem cells through modulation of multiple oncogenic targets Cenciarelli, C., Marei, H.E., Zonfrillo, M., …Althani, A., Mangiola, A. Oncotarget, 2017, 8(11), pp. 17873–17886	Oncotarget	5.168	2018
   40	The-effect-of-triiodothyronine-on-maturation-and-differentiation-of-oligodendrocyte-progenitor-cells-during-remyelination-following-induced-demyelination in male albino rat” (Tissue and Cell (2016) 48(3) (242–251) (S0040816615300495) (10.1016/j.tice.2016.03.001)) El-Tahry, H., Marei, H.E., Shams, A., …Abdelaziz, H., El-kader, M.A. Tissue and Cell, 2016, 48(6), pp. 659	Tissue and Cell	1.438	2016
   41	Therapeutic potential of human olfactory bulb neural stem cells for spinal cord injury in rats Marei, H.E., Althani, A., Rezk, S., …Cenciarelli, C., Caceci, T. Spinal Cord, 2016, 54(10), pp. 785–797	Spinal Cord	1.936	2016
   42	Human Microbiome and its Association With Health and Diseases Althani, A.A., Marei, H.E., Hamdi, W.S., …Abdel-Aziz, H., Cenciarelli, C. Journal of Cellular Physiology, 2016, 231(8), pp. 1688–1694	Journal of Cellular Physiology	3.923	2016
   43	Common and Rare Genetic Variants Associated With Alzheimer’s Disease Marei, H.E., Althani, A., Suhonen, J., …Wang, T., Caceci, T. Journal of Cellular Physiology, 2016, 231(7), pp. 1432–1437	Journal of Cellular Physiology	3.923	2016
   44	Landscape of NAT2 polymorphisms among breast cancer Wang, T., Marei, H.E. Biomedicine and Pharmacotherapy, 2016, 77, pp. 191–196	Biomedicine and Pharmacotherapy	3.457	2016
   45	Pseudomonas aeruginosa: Arsenal of resistance mechanisms, decades of changing resistance profiles, and future antimicrobial therapies El Zowalaty, M.E., Al Thani, A.A., Webster, T.J., …Marei, H.E., Ashour, H.M. Future Microbiology, 2015, 10(10), pp. 1683–1706	Future Microbiology	3.190	2017
   46	Human olfactory bulb neural stem cells mitigate movement disorders in a rat model of Parkinson’s disease Marei, H.E.S., Lashen, S., Farag, A., …Casalbore, P., Cenciarelli, C. Journal of Cellular Physiology, 2015, 230(7), pp. 1614–1629	Journal of Cellular Physiology	3.923	2016
   47	Human olfactory bulb neural stem cells expressing hNGF restore cognitive deficit in Alzheimer’s disease rat model Marei, H.E.S., Farag, A., Althani, A., …Casalbore, P., Cenciarelli, C. Journal of Cellular Physiology, 2015, 230(1), pp. 116–130	Journal of Cellular Physiology	3.923	2016
   48	PDGF receptor alpha inhibition induces apoptosis in glioblastoma cancer stem cells refractory to anti-Notch and anti-EGFR treatment Cenciarelli, C., Marei, H.E.S., Zonfrillo, M., …Maira, G., Mangiola, A. Molecular Cancer, 2014, 13(1), 247	Molecular Cancer	7.776	2017
   49	Localization of S-100 proteins in the testis and epididymis of poultry and rabbits Abd-Elmaksoud, A., Shoeib, M.B., Marei, H.E.S. Anatomy and Cell Biology, 2014, 47(3), pp. 180–187	Anatomy and Cell Biology	0.73	2014
   50	Over-expression of hNGF in adult human olfactory bulb neural stem cells promotes cell growth and oligodendrocytic differentiation Marei, H.E.S., Althani, A., Afifi, N., …Casalbore, P., Cenciarelli, C. PLoS ONE, 2013, 8(12), e82206	PLoS ONE	3.534	2013
   51	Transcription factors expressed in embryonic and adult olfactory bulb neural stem cells reveal distinct proliferation, differentiation and epigenetic control Marei, H.E.S., Ahmed, A.-E. Genomics, 2013, 101(1), pp. 12–19	Genomics	2.793	2013
   52	Gene expression profile of adult human olfactory bulb and embryonic neural stem cell suggests distinct signaling pathways and epigenetic control Marei, H.E.S., Ahmed, A.-E., Michetti, F., …Cenciarelli, C., Elhadidy, M. PLoS ONE, 2012, 7(4), e33542	PLoS ONE	3.730	2013
   53	Gene expression profiling of embryonic human neural stem cells and dopaminergic neurons from adult human substantia nigra Marei, H.E.S., Althani, A., Afifi, N., …Schwartz, P., Ahmed, A.-E. PLoS ONE, 2011, 6(12), e28420	PLoS ONE	4.092	2011
   54	Morphological and glycohistochemical studies on the epididymal region of the Sudani duck (Cairina moschata) Abd-Elmaksoud, A., Sayed-Ahmed, A., Mohamed, S.E., Mohamed, K., Marei, H.E. Research in Veterinary Science, 2009, 86(1), pp. 7–17	Research in Veterinary Science	1.345	2009
   55	Fine structural and immunohistochemical localization of cardiac hormones (ANP) in the right atrium and hypothalamus of the white rat Marei, H.E.S. European Journal of Morphology, 2002, 40(1), pp. 37–41	European Journal of Morphology	0.342
   56	Differentiation of ciliated cells in the terminal bronchioles of neonatal calves Marei, H.E.S., El-Gawad, M.A. European Journal of Morphology, 2001, 39(5), pp. 269–276	European Journal of Morphology	0.622	2001
   57	Observations on rodlet cells found in the vascular system and extravascular space of angelfish (Pterophyllum scalare scalare) Smith, S.A., Caceci, T., Marei, H.E‐S., El‐Habback, H.A. Journal of Fish Biology, 1995, 46(2), pp. 241–254	Journal of Fish Biology	0.918	1995
   58	Xeno-free trans-differentiation of adipose tissue-derived mesenchymal stem cells into glial and neuronal cells. Elgamal A, Althani A A, Abd-Elmaksoud A, Kassab M, Farag A, Lashen S, Gabr MM, Zakaria MM, Alissawi MM, Ismail HEA, Abd El Galil A, Caceci T, Cenciarelli C C, Marei HE. Am J Stem Cells. 2019 Aug 15;8(2):38-51. eCollection 2019	Am J Stem Cells	0.34	2019
   	Total		222.41

International Book Chapter:

1. Marei HE, Asmaa Althani, Mohamed El Zowalaty, Carlo Cenciarelli (2015) Recent perspective about the amyloid cascade hypothesis and stem cell-based therapy in the treatment of Alzheimer’s disease (Accepted for publication as a book chapter with Bentham Science Publishers (eBook series “Frontiers in Clinical Drug Research-Alzheimer Disorder; Vol. 4”).

International Books:

1. Marei HE, Human Olfactory Bulb Neural Stem Cells for Cell-based Therapy of Traumatic and Neurodegenerative CNS Disorders, LAMBERST, 2016.

Topic Guest Editor for ongoing International E-Books:

1. Recent Prospective in CAR T-based Therapy for Solid and Hematological Malignancies. Biomedicine (impact Factor 6.081). Topic Editors: Marei HE, and Carlo Cenciarelli:

2. Inflammation in Ischemic Stroke and Novel Therapeutic Strategies for Stroke Treatment. Topic Editors: Marei HE, Changjun Yang, Carlo Cenciarelli, Assia Jaillard.

Book Chapter:

1. Marei HE, Asmaa Althani, Mohamed El Zowalaty, Carlo Cenciarelli (2015) Recent perspective about the amyloid cascade hypothesis and stem cell-based therapy in the treatment of Alzheimer’s disease (Accepted for publication as a book chapter with Bentham Science Publishers (eBook series “Frontiers in Clinical Drug ResearchAlzheimer Disorder; Vol. 4”).

Books:

1. Marei HE, Human Olfactory Bulb Neural Stem Cells for Cell-based Therapy of Traumatic and Neurodegenerative CNS Disorders, LAMBERST, 2016.

Theses Supervision:

Master Thesis Supervision

1. Ontogeny of Primary Immune Organs in Some Chickens Breeds Ontogeny of thymus and spleen in Camel’s (Faculty of Veterinary Medicine, Mansoura Univesity, Egypt). Finished.
2. Effects of seasonal variation on the histological structure of the accessory male glands of the camel (Camelus dromedaries). (Faculty of Veterinary Medicine, Mansoura Univesity, Egypt). Finished.
3. Pre- and post-hatching development of Harderian gland and Bursa of Fabricius in Chicken. (Faculty of Veterinary Medicine, Mansoura University, Egypt). Finished.
4. Histological Studies of the Digestive System of Oreochromis niloticus using Virtual Microscopy. (Faculty of Veterinary Medicine, Mansoura Univesity, Egypt). Finished.
5. Effects of seasonal variation on the histological; structures of gonads in Oreochromis niloticus. (Faculty of Veterinary Medicine, Mansoura Univesity, Egypt). Finished.
6. Genomic and Immunohistochemical Study for Assessment of Therapeutic Potential of Human Olfactory Bulb Neural Stem Cells in Spinal Cord Rat Model. (Faculty of Veterinary Medicine, Mansoura University, Egypt). Completed 2012.
7. Effects of oligomeric and fibrillar β-amyloid on proliferation and differentiation of human olfactory bulb neural stem cells. Collage of Health Sciences, Qatar University, Qatar). Expected defense date 2017.
8. Neuroprotective effects of small interfering RNA (siRN) against amyloid β-induced neurotoxic pathways in human olfactory bulb neural stem Cells. Collage of Health Sciences, Qatar University, Qatar). Expected defense date 2017.
9. Neuronal differentiation potential of mesenchymal stem cells derived from human adipose tissue. Completed, August 2016
10. Differentiation of human olfactory bulb neural stem cell into oligodendrocytes. Completed, August 2016. Completed, August 2016
11. Nanotubes impregnated human olfactory bulb neural stem cells promote neuronal differentiation in Trimethyltin-induced neurodegeneration rat model. Completed, August 2016.
12. RNA-sequencing of the human iPSC-derived-astrocyte (Collage of Health Sciences, Qatar University, 2016-2018).
13. Transcriptome analysis of human iPSC-derived neurons (Collage of Health Sciences, Qatar University, 2016-2018).

PhD Thesis Supervision

1. Differentiation of Cattle’s mesenchymal stem cell: Electron Microscopy, Immunohistochemical and Molecular Studies. (Faculty of Veterinary Medicine, Mansoura University, Egypt). Expected defense date 2013.
2. Genomic and Immunohistochemical Study for Assessment of Therapeutic Potential of Human Olfactory Bulb Neural Stem Cells in Alzheimer’s Rat Model. (Faculty of Veterinary Medicine, Mansoura University, Egypt). Finished
3. Genomic and Immunohistochemical Study for Assessment of Therapeutic Potential of Human Olfactory Bulb Neural Stem Cells in Parkinsonian’s Rat Model (Faculty of Veterinary Medicine, Mansoura University, Egypt). Finished
4. Histological Evaluation for The Use of Nanotubes Impregnated Human Olfactory Bulb Neural Stem Cells for TMT– induced Neurodegeneration in Rats. (Faculty of Veterinary Medicine, Mansoura University, Egypt). Finished
5. Potentialities of Neural Stem Cell-based Therapy in Spinal Cord Injury of Rats : Immunohistochemical Study. (Faculty of Veterinary Medicine, Mansoura University, Egypt). Finished
6. Immunohistochemical Assessment of Neural Stem Cell-based Therapy in Alzheimer. (Faculty of Veterinary Medicine, Mansoura University, Egypt). Finished.
7. Immunohistochemical Assessment of Neural Stem Cell-based Therapy in Parkinsonian. (Faculty of Veterinary Medicine, Mansoura University, Egypt). Finished.

Funded Projects:

Educational Enhancement Projects:

1. Enhancement of Education and Development of Distance Learning Resources for Image-Based (Histology, Pathology, Radiology) courses, code number C-024-L0, funded by HEEPF (Higher Education Enhancement Project Fund, Egypt), $ 38000. Web site: www.vetmansoura.com.
2. Enhancement of Veterinary Undergraduate Students Assessment System ” Funding Agency: Program of Continuous Improvement and Qualification for Accreditation in HEI (PCIQA), Fund Approved 1000 000 LE ($ 145 000), Duration: 24 months, 2006-2007
3. Continuous Improvement and Qualification of Faculty of Veterinary Medicine, Mansoura University for Accreditation” Program of Continuous Improvement and Qualification for Accreditation in HEI (PCIQA), Fund Approved 4000 000 LE ($580000), 2010-2013

Stem Cell Research Project:

1. Adult Human Olfactory Bulb Neural Stem Cells for Cell-based Therapies in The Central Nervous System”, Science and Technology Development Fund (STDF), 1000 000 LE ($ 145 000), 2009-2014.

Lab Accreditation and ISO Projects:

1. Accreditation of Molecular Biology Unit Standards at the Central lab of Faculty of Veterinary Medicine, Mansoura University According to ISO 17025, $145000, 2014-2016.
2. Development of Human Resources Units and its Accreditation according to ISO 9001 Standards and Development of Joint Doctor of Veterinary Medicine (DVM)-like Bachelor’s Degree according to American Veterinary Medical Association (AVMA) Standards, $580000), 2014-2017.

NPRP (National Priority Research Program), Qatar Foundation:

NPRP9-144-3-021: A Novel Angiogenic Anti-microbial Patch for Diabetic Wounds and Ulcer Treatment, PI, $718,412.00

UREP (Undergraduate Research Experience Program), Qatar Foundation

UREP19-100-1-011Research Mentor in the proposal UREP19-100-1011 Title: Synthesis, Characterization & In vitro Biological Activity of pd(II) & Ln(III) Thiosemicarbazone, $10,000

Research Mentor in UREP20-086-3-025: Title: Outcome of cell phone radiofrequency on the initiation and progression of human head and neck cancers.

Research Mentor in UREP19-100-1-011: Title:Synthesis, Characterization & In vitro Biological Activity of pd(II) & Ln(III) Thiosemicarbazone.

Internal Grant, Qatar University:

QUUG-BRC-BRC- 15\16-2: Targeting Glioblastoma Cancer Cells Using Paclitaxel-Loaded Human iPSCs-derived Neural Stem Cell” has been approved for a total amount of QR 120,000, Project duration starting from 28\02\2016 and is valid until 31\12\2017.

International Workshop, Qatar Foundation

CWSP8-W-0916-15017: Molecular Epidemiology of Key Global Priorities: Antimicrobial Resistance and Emerging Zoonotic Virus. $49,800.00

GCC-2017-004: Use of patient-specific induced pluripotent stem cells (iPSCs) to study stroke in Qatar and GCC countries. PI, Lead, $480,000, Project duration starting from 1\12\2016 and is valid until 30\11\2019.

GCC-2017-005: A Novel GelMA Hydrogel based Microfluidic Blood-Brain Barrier Prototype for in vitro Studies of Cancer Metastasis. Co-PI, $480,000, Project duration starting from 1\12\2016 and is valid until 30\11\2019.

2015-present Conferences, Speaker, Poster, seminars, and workshops:

1. Workshop: Flow Cytometry Experiment Design and Data Analysis, 26th November 2015, Biomedical Research Center, Qatar University.
2. International Conference: Human Olfactory Bulb Neural Stem Cell Based Therapy For CNS Traumatic and Neurodegenerative Diseases, World Stem Cell Summit, Atlanta, Georgia, 2015, USA. The poster has been selected for Honorable Mention during this conference.
3. Seminar: Personalized Anticoagulant Management. 10th December 2015, Biomedical Research Center, Qatar University.
4. Seminar: The Host-Microbe Interface: from a single pathogen to a microbiome, 16th December 2015, Biomedical Research Center, Qatar University.
5. Seminar: Use of Aptamer Nanotechnology in Targeting Cancer Stem Cells, 24th December 2015, Biomedical Research Center, Qatar University.
6. Seminar: Stem Cell and Regenerative Medicine, 18th February 2016, Biomedical Research Center, Qatar University.
7. Seminar: Investigation of Mechan-Biological Factors Contributing to Congenital heart defects, 23rd February 2016, Biomedical Research Center, Qatar University.
8. Seminar: Rapid Molecular Techniques for Identification of Gram Positive Cocci Directly from Blood cultures, 1st March 2016, Biomedical Research Center, Qatar University.
9. Seminar: Why does rapid diagnostic infectious disease testing matter? 17th March 2016, Biomedical Research Center, Qatar University.
10. Seminar: Combined immunodeficiency associated with homozygous MALT1 mutations, 28th April 2016, Biomedical Research Center, Qatar University.
11. Seminar: Functional Molecular Diagnostic (FMDx) for personalization of cancer treatment – research and clinical results, 5th May 2016, Biomedical Research Center, Qatar University.
12. Seminar: Cerebrospinal fluid biomarkers in Parkinson disease, Biomedical Research Center, Qatar University.
13. Poster Presentation entitle” Human Olfactory Bulb Neural Stem Cells for Cellular-based Therapy of Neurodegenerative Diseases, Annual Research Day (ARC’2016) QNCC, March, 2016, Qatar National Convention Center, Doha, Qatar. Poster selected within the top 10 position from more than 1500 submitted posters.
14. Handling Genomic Data: Clinical Interpretation, Governance and Responsible Sharing” 17th–18th April, 2016, Qatar National Convention Center, Doha, Qatar.
15. Cancer Genomics Program: Qatar Molecular Profiling Workshop. April 27-28th @ NCCCR, Qatar.
16. Poster Presentation entitle” Human Olfactory Bulb Neural Stem Cells for Cellular-based Therapy of Neurodegenerative Diseases The Qatar University Annual Research Forum, May 3, 2016, Research Complex, Qatar University.
17. Advisory Committee of Biomedical Research Center Meeting for discussion of future strategic plan for enhancing biomedical research at BRC. May 3rd, 2016 @ BRC, Qatar University, Qatar.
18. COMSTECH-FCC Joint International Workshop on Genomics & Genome Editing, Forman Christian College, Lahore, Pakistan, May 24-27, 2016.
19. Workshop :Tissue Culture of Mammalian Cells”, presenter, Biomedical Research Center, Qatar University, August, 2016.
20. International Workshop: Human Animal interface and emerging pathogens”, Biomedical Research Center, Qatar University, October, 2016.
21. Speaker and presentation (Drugs treatment and gene expression analysis to target Glioblastoma cancer stem cells: towards a personalized medicine for brain cancer (GBM) “3rd Middle East Molecular Biology Congress and Exhibition ” 14 -17 November 2016, Research Complex, Qatar University.
22. Speaker and presentation (Pre-clinical evidence for successful engraftment of human olfactory bulb neural stem cells for Alzheimer’s, Parkinson’s and spinal cord injury) in “2nd International Conference on Brain Disorders and Therapeutics during October 26-28, 2016 at Chicago, USA.”
23. Workshop, WuXi NextCODE Genomic training for local researchers, 8-9 November, 2016, Sidra, Doha, Qatar.
24. Workshop: Digital Western Blot”, Biomedical Research Center, Qatar University, November, 5, 2016.
25. Workshop: “Octet System and its application in Biomedical Researches”, Biomedical Research Center, Qatar University, November, 17, 2016.
26. Poster (PDGFRα depletion attenuates glioblastoma stem cells features by modulation of STAT3, RB1 and multiple oncogenic signals) in “12th World Stem Cell Summit during DECEMBER 6-9, 2016, WEST PALM BEACH, FLORIDA, USA.”
27. Functional Genomics Symposium Nature via Nurture, a workshop on scientific topic in collaboration with Sidra Medical & Research center on 14th December in Sidra out Patient Clinic (OPC), Doha, Qatar.
28. Speaker and presentation (Human Olfactory Bulb Neural Stem Cells for Cell-Based Therapy of Alzheimer’s Disease in Rats) in Seventh International Conference on Alzheimer’s Disease and Related Disorders in the Middle East (ICAD-ME), Abu Dhabi, United Arab Emirates, February 23-25, 2017.
29. Keynote speaker and presentation (Stem Cells Research in Sport) in Sports and Genetics Symposium, Doha, Qatar, April 17, 2017.
30. Seminar: Small vessel disease and the risk of ischemic stroke. Experience from Qatar Stroke Database, 20th of April 2017, Collage of Health Sciences, Qatar University, Doha, Qatar.
31. Member of Organizing Committee: Second Annual Health Research Symposium at Qatar University, 22nd of April, 2017, College of Medicine, Qatar University, Doha, Qatar.
32. 1st QBRI Autism Symposium, April 30th – May 1st/2017 Venue: Qatar National Convention Center (QNCC), Qatar Foundation, Doha – Qatar.
33. 9th Annual Forum of Qatar National Research Fund, June 14th, 2017. Qatar National Convention Center (QNCC), Qatar Foundation, Doha – Qatar.
34. NCURA Fundamentals of Sponsored Project Management, September 12-14, 2017, New Research Complex (NRC), Qatar University, Qatar.
35. Speaker and presentation (Nanotubes impregnated human olfactory bulb neural stem cells promote neuronal differentiation in Trimethyltin-induced neurodegeneration rat model, 9th Annual Conference on Stem Cell and Regenerative Medicine, Sep 25-26, 2017 Berlin, Germ Germany. Theme: Frontiers in Stem Cells & Regeneration.
36. Speaker and presentation (Prospect of human Olfactory Bulb NSC for Cell-based therapy), Tissue Engineering and Stem Cell Technologies Workshop (CPD accredited), October 25-26, 2017 New Research Complex, Qatar University, Doha.
37. Attending, Advanced Therapies in Healthcare, Sidra Medical and Research Center, Four Seasons Hotel, Doha, Qatar.
38. Moderator for COPHAI 2017 Pre-Congress Workshop – Doha, Qatar, November 6, 2017.
39. Attending, Fourth International Conference for Pathogens at Human Animal Interface, Retz Carlton Hotel, Doha, Qatar 7-9 November, 2017.

Awards and honors

1. Winners of the Readers’ Choice Award for original research papers published in 2016 for their Original Article Therapeutic potential of human olfactory bulb neural stem cells for spinal cord injury in rats (Spinal Cord (2016) 54, 785-797; doi: 10.1038/sc.2016.14)
2. Winner of Best Poster Award, Annual Research Day, Qatar University, March 2016.
3. Best Poster Award, ARC’2016, National Qatar Exhibition Center (NQEC), May 2016.
4. World Stem Cell Summit 2015 (10-12 December 2015) in Atlanta – USA. Honorable Mention during this conference for poster about OBNSC.
5. First Place Award of Excellence in Scientific Research, Ministry of Higher Education, Egypt (2012).
6. Mansoura University Encouraging Award (May 2004)
7. Man of the year 2014 nominated by Faculty Counsel, Faculty of Veterinary Medicine, Mansoura University, Egypt.
8. Marquis Who’s Who, 2013

References

Asma Ali J F Althani, PhD

Dr. Thomas Caceci

Prof. Fabrizio Michetti, M.D.,